A typical workflow with CHANCE. CHANCE can provide a scientist with feedback regarding the success of their experiment, as well as how their protocols may be improved. CHANCE is designed to work with reads mapped to a reference genome. The dotted pink region illustrates the useful quality metrics computed by CHANCE to assess a ChIP-seq experiment. One can use these intuitive results to determine if the experiment is satisfactory or if additional protocol modification or sequencing is required.
Diaz et al. Genome Biology 2012 13:R98 doi:10.1186/gb-2012-13-10-r98