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Dicer partners expand the repertoire of miRNA targets

Lukasz Jaskiewicz and Mihaela Zavolan*

Author Affiliations

Biozentrum, University of Basel and Swiss Institute of Bioinformatics, Klingelbergstr. 50/70, CH-4056, Basel, Switzerland

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Genome Biology 2012, 13:179  doi:10.1186/gb-2012-13-11-179

Published: 29 November 2012

Abstract

Processing of pre-miRNAs by Dicer is regulated by its dsRNA-binding protein partner, and leads to the generation of alternative miRNA forms with distinct target sets.