MIRAGE's predictive performance on reconstructing a known metabolic network of the cyanobacteria Synechocystis sp. PCC6803. (a) Metabolic network after Knoop et al. ; (b) metabolic network after Montagud et al. [51,52]. The precision and recall of MIRAGE is marked with a star symbol. The precision and recall of a variant of MIRAGE that does not utilize functional-genomics data is marked with a circle. The predictive performance of the functional genomic data (without metabolic flux analysis) is shown by the purple line. The performance of random predictions of gap-filling reactions is colored blue.
Vitkin and Shlomi Genome Biology 2012 13:R111 doi:10.1186/gb-2012-13-11-r111