Open Access Research

Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data

Matthew Parker1, Xiang Chen1, Armita Bahrami2, James Dalton2, Michael Rusch1, Gang Wu1, John Easton3, Nai-Kong Cheung4, Michael Dyer5, Elaine R Mardis67, Richard K Wilson67, Charles Mullighan2, Richard Gilbertson5, Suzanne J Baker5, Gerard Zambetti8, David W Ellison2, James R Downing2, Jinghui Zhang1* and the Pediatric Cancer Genome Project

Author Affiliations

1 Department of Computational Biology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA

2 Department of Pathology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA

3 The Pediatric Cancer Genome Project, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA

4 Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA

5 Department of Developmental Neurobiology, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA

6 The Genome Center at Washington University, Washington University, 4444 Forest Park Ave, St Louis, Missouri 63108, USA

7 Department of Genetics, Washington University, 4444 Forest Park Ave, St Louis, Missouri 63108, USA

8 Department of Biochemistry, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA

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Genome Biology 2012, 13:R113  doi:10.1186/gb-2012-13-12-r113

Published: 11 December 2012

Additional files

Additional file 1:

Supplementary figures.

Format: DOCX Size: 40KB Download file

Open Data

Additional file 2:

Telomere calls for WGS, qPCR and FISH (where appropriate) for all of the samples analyzed in this manuscript.

Format: XLS Size: 61KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data