Table 1

Sources of noise and their effect on interaction scores

Noise affects score?


Source of noise

Static score

dS score


Double/single mutant ratio, pre-DM selection

Double/single mutant ratio, DM selection

Uneven agar surface, pre-DM selection

Uneven agar surface, DM selection

Variation in environment, pre-DM selection

Variation in environment, DM selection


DM, Double Mutant

Bean and Ideker Genome Biology 2012 13:R123   doi:10.1186/gb-2012-13-12-r123

Open Data