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Highly Accessed Review

Synthetic biology: advancing biological frontiers by building synthetic systems

Yvonne Y Chen12, Kate E Galloway3 and Christina D Smolke4*

Author affiliations

1 Society of Fellows, Harvard University, 78 Mount Auburn St, Cambridge, MA 02138, USA

2 Department of Systems Biology, Harvard Medical School, 200 Longwood Ave, WAB 536, Boston, MA 02115, USA

3 Division of Chemistry and Chemical Engineering, California Institute of Technology, 1200 East California Blvd, MC 210-41, Pasadena, CA 91125, USA

4 Department of Bioengineering, Stanford University, 473 Via Ortega, MC 4201, Stanford, CA 94305, USA

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Citation and License

Genome Biology 2012, 13:240  doi:10.1186/gb-2012-13-2-240

Published: 20 February 2012

Abstract

Advances in synthetic biology are contributing to diverse research areas, from basic biology to biomanufacturing and disease therapy. We discuss the theoretical foundation, applications, and potential of this emerging field.