Regulation of NBs relies heavily on PTGR mechanisms. (a-f) Smed-H2B(RNAi) IS versus irradiation IS plot of the transcripts compiled with KEGG (BRITE hierarchies) transcription factors (a, magenta), KEGG pathways 'RNA polymerase' and 'Basal transcription factors' (b, blue), KEGG pathway 'Spliceosome' (c, red), KEGG pathway 'RNA transport' (d, green), KEGG pathway 'mRNA surveillance' (e, yellow) and KEGG pathway 'RNA degradation' (f, cyan). Green horizontal lines represent the median Smed-H2B(RNAi) IS of each compilation. Several transcription factors are found in our list of NB-expressed transcripts, but they are not significantly enriched (a), and similarly, transcription machinery is not significantly enriched either (b). However, a strong enrichment is found for spliceosome components (c). Other RNA-associated processes, such as RNA transport (d), mRNA surveillance (e) and RNA degradation (f), are enriched as well with various significances.
Solana et al. Genome Biology 2012 13:R19 doi:10.1186/gb-2012-13-3-r19