Figure 7.

Dynamics of category 1 to 4 markers in irradiated and Smed-H2B(RNAi) samples. (a-d) Dynamics of category 1 (a), 2 (b), 3 (c) and 4 (d) transcript expression in irradiated samples (left) and Smed-H2B(RNAi) samples (right) relative to non-irradiated (left) and control(RNAi) (right) samples. All categories of transcripts downregulated by irradiation described by Eisenhoffer and co-workers [24] are consistently downregulated by day 7 after irradiation in our dataset (right). Only category 1 markers (a, right) are dowregulated progressively without peaking at any time point after Smed-H2B RNAi. Category 2 and 3 transcripts display a peak in Smed-H2B(RNAi) samples and category 4 transcripts are not downregulated as a whole.