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Regulation of transcriptome, translation, and proteome in response to environmental stress in fission yeast

Daniel H Lackner13, Michael W Schmidt2, Shuangding Wu2, Dieter A Wolf2 and Jürg Bähler1*

Author Affiliations

1 Department of Genetics, Evolution and Environment and UCL Cancer Institute, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK

2 Signal Transduction Program, Sanford-Burnham Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA

3 The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037-1099, USA

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Genome Biology 2012, 13:R25  doi:10.1186/gb-2012-13-4-r25

Published: 18 April 2012

Additional files

Additional file 1:

Data of all mRNA and translation ratios (Figure 2), and data from translational profiling analysis (percentage RNA in each fraction, sum of differences, and scores (Figure 1c).

Format: XLSX Size: 7.4MB Download file

Open Data

Additional file 2:

Annotated list of genes in clusters 1 to 3 (Figure 2).

Format: XLS Size: 163KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Annotated list of translationally regulated genes in three stress conditions (Table 1).

Format: XLS Size: 77KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

Proteomics data including raw spectrum count measurements, normalized averaged data and list of significantly changed proteins; mRNA data obtained in parallel are also included.

Format: XLSX Size: 1.3MB Download file

Open Data

Additional file 5:

Annotated list of genes showing discordant regulation at mRNA and protein levels.

Format: XLS Size: 53KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data