Figure 1.

Effect of diet on host transcriptional responses. Genes known a priori to be involved in intestinal biology or immunity and defense mechanisms were enriched for differential expression between BF and FF infants. (a-d) The distribution of P-values (a,b) and the distribution of q-values (c,d). (a,c) Intestinal biology: 459 genes known to be related to intestinal biology passed the quality control measures and were tested for differential expression between the BF and FF infants - 146/459 genes (32%) had FDR corrected q-values <0.2. (b,d) Immunity and defense: 660 genes known to be related to immunity and defense that passed the quality control measures and tested for differential expression between the BF and FF infants - 191/660 genes (29%) had FDR corrected q-values <0.2.