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Transposable elements: not as quiet as a mouse

Rita Rebollo12, Ying Zhang12 and Dixie L Mager12*

Author Affiliations

1 Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, BC, V5Z1L3 Canada

2 Department of Medical Genetics, University of British Columbia, Vancouver, BC, V6H 3N1 Canada

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Genome Biology 2012, 13:159 doi:10.1186/gb-2012-13-6-159

Published: 20 June 2012

Abstract

In this issue of Genome Biology, Nellåker et al. show massive purging of deleterious transposable element variants, through negative selection, in 18 mouse strains.

Keywords:
Transposable elements; variants; mouse strains; next-generation sequencing; evolution; natural selection; comparative genetics