The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities
1 Institute of Genetic Medicine, Newcastle University, NE1 3BZ, UK
2 Clinician Investigator Program, University of British Columbia, Vancouver, BC V6Z 1Y6, Canada
3 MRC Unit for Lifelong Health & Aging, London, WC1B 5JU, UK
4 MRC Centre for Causal Analyses in Translational Epidemiology (CAiTE), School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK
Genome Biology 2012, 13:246 doi:10.1186/gb-2012-13-6-246Published: 29 June 2012
Longitudinal cohort studies are ideal for investigating how epigenetic patterns change over time and relate to changing exposure patterns and the development of disease. We highlight the challenges and opportunities in this approach.