Methylomic profiling across multiple brain areas and blood from a cohort of individuals highlights clear tissue-specific differences in DNA methylation. (a, b) DNA methylation was calculated from ultra-deep MeDIP-seq data using 500 bp bins across the genome, and the relationship between tissues determined by Pearson correlation (a) and unsupervised hierarchical clustering (b). BA, Brodmann area; Ent Ctx, entorhinal cortex; STG, superior temporal gyrus; Vis Ctx, visual cortex.
Davies et al. Genome Biology 2012 13:R43 doi:10.1186/gb-2012-13-6-r43