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The greatest catch: big game fishing for mRNA-bound proteins

Christopher R Sibley, Jan Attig and Jernej Ule*

Author Affiliations

MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK

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Genome Biology 2012, 13:163  doi:10.1186/gb-2012-13-7-163

Published: 17 July 2012

Abstract

Purification of proteins cross-linked to mRNAs has identified 800 mRNA-binding proteins and their characteristics.

Keywords:
CLIP; 4-thiouridine; RBP; RNA-binding domain; disordered proteins