Research
Developmental features of DNA methylation during activation of the embryonic zebrafish genome
1 Stem Cell Epigenetics Laboratory, Institute of Basic Medical Sciences, Faculty of Medicine, and Norwegian Center for Stem Cell Research, University of Oslo, PO Box 1112 Blindern, 0317 Oslo, Norway
2 BasAM, Norwegian School of Veterinary Science, PO Box 8146 Dep., 0033 Oslo, Norway
Genome Biology 2012, 13:R65 doi:10.1186/gb-2012-13-7-r65
Published: 25 July 2012Additional files
Additional file 1:
Promoter DNA methylation in zebrafish embryos and sperm. A figure showing aspects of promoter methylation in zebrafish embryos and sperm.
Format: PDF Size: 657KB Download file
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Additional file 2:
Enriched GO terms for methylated and hypomethylated genes. An Excel sheet of enriched GO terms for methylated and hypomethylated genes.
Format: XLS Size: 112KB Download file
This file can be viewed with: Microsoft Excel Viewer
Additional file 3:
CG content analysis of zebrafish promoters. A figure showing the CG content analysis of zebrafish promoters.
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Additional file 4:
Partitioning of tiled regions reveals developmentally linked dynamic methylation upstream of TSS. A figure showing methylation profiles in -1 to -1 kb regions around the TSS.
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Additional file 5:
Enriched GO terms of hypomethylated genes found in CGI clusters and methylated in ZF4 fibroblasts. A table of enriched GO terms for hypomethylated genes in CGI clusters and that are methylated in ZF4 cells.
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Additional file 6:
Differential methylation of multiple versus single CGI promoters in embryos and ZF4 cells. A figure showing methylation profiles of the hoxa and bact1 loci in post-MBT embryos and in ZF4 cells.
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Additional file 7:
Bisulfite sequencing primers used in this study. A table of bisulfite sequencing primers used in this study.
Format: PDF Size: 79KB Download file
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Additional file 8:
Primers used for MeDIP-qPCR validation. A table of primers used for MeDIP-qPCR validation in this study.
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