Figure 6.

Promoter marking by modified histones before ZGA onset is associated with enhanced gene expression potential after ZGA. Graph shows the percentage of expressed genes (≥5 RNA-seq reads) at or after the MBT (post-ZGA) as a function of promoter DNA methylation state and marking by H3K4me3, H4K9me3 or H3K27me3 at the pre-MBT or MBT stages. **P < 10^-5; *P < 0.001; ^-P = 0.058 (Chi-square test with Yate's correction).