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Resolution: standard / high Figure 1.
Framework for assessing confidence in a HTP PPI screen. Coev2Net, trained on a high-quality PPI network, is able to assign structure-based
confidence scores for HTP PPI networks. Each node represents a protein and each edge
the putative interaction between the two proteins. The thickness of an edge describes
structure-based confidences of putative PPIs.
Hosur et al. Genome Biology 2012 13:R76 doi:10.1186/gb-2012-13-8-r76 |