Human pigmentation genes under environmental selection
1 Institute for Molecular Bioscience, Melanogenix Group, The University of Queensland, Brisbane, Qld 4072, Australia
2 Queensland Institute of Medical Research, Brisbane, Qld 4029, Australia
Genome Biology 2012, 13:248 doi:10.1186/gb-2012-13-9-248Published: 27 September 2012
Genome-wide association studies and comparative genomics have established major loci and specific polymorphisms affecting human skin, hair and eye color. Environmental changes have had an impact on selected pigmentation genes as populations have expanded into different regions of the globe.