Cell type-specific binding of TCF7L2. (a,b) The ChIP-seq binding patterns of TCF7L2 are compared in six cell lines, demonstrating both common peaks (a) and cell type-specific binding (b). (c) The ChIP-seq binding patterns of TCF7L2 near and within the SH3BP4 locus is shown for three cell lines. The number of tags reflecting the ChIP enrichments are plotted on the y-axis; the chromosomal coordinates (hg19) shown are: (a) chr19:7,701,591-7,718,750; (b) chr1:112,997,195-113,019,766; and (c) chr2:235,767,270-235,974,731.
Frietze et al. Genome Biology 2012 13:R52 doi:10.1186/gb-2012-13-9-r52