Figure 5.

Metabolic flux predictions by different methods in environmentally perturbed E. coli wild-type strains. (a-d) The flux distribution of wild type grown aerobically on glucose in a batch (a,b) or chemostat (c,d) culture was used as a reference state to predict fluxes in galactose medium (a), glucose anaerobic condition (b), acetate medium (c), and chemostat (d) at different dilution rates. The RELATCH predictions were made using the tight parameter values for (a) or the relaxed parameter values for (b-d).