Table 1

PERMANOVA test for significance of factors contributing to overall differences in microbiota composition

Phylum

Class

Family

Genus

OTU


Genotype

2.00E-07

2.00E-07

2.00E-07

2.00E-07

2.00E-07

Cage

0.0238

5.08E-05

7.26E-05

6.20E-06

2.00E-07

Sex

0.44

0.2972

0.3003

0.3926

0.2456

Sex_block

0.374

0.09805

0.1091

0.2072

0.05531


Genotype and cage were significantly associated with differences in microbiota composition whereas sex did not have an effect. Note that only B6 mice were used to test for sex effects as we only had females and males from B6. We repeated the PERMANOVA test for the complete dataset, using genotype in a blocked design to test for sex effects (sex_block). We used 5 × 107 permutations to calculate the significances.

Hildebrand et al. Genome Biology 2013 14:R4   doi:10.1186/gb-2013-14-1-r4

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