Additional file 5: Figure S3.
(A) ChIP enrichment of individual subunits is averaged across TSSs, indicating an enrichment of binding at promoters for each subunit. (B) Transcription factors (TFs) whose sites are reported at the modENCODE consortium data coordination center are ranked by the fold enrichment of overlap with condensin binding sites. Those TF sites and condensin sites that overlap with HOT regions are removed from this analysis. Fold enrichment is calculated by random redistribution of condensin binding sites 10,000 times across the genome and calculating the ratio of percent overlap in observed versus average of random distributions. (C) Percent overlap between TFs and condensins. For 'condensin’ columns, data indicate percentage of condensin sites that overlap with each TF (rows). For columns labeled 'TF’, data indicate percentage of TF sites that overlap with condensin. Data on the left panel for condensin I-IDC is from the X chromosome only. Data on the right panel for condensin II is from the whole genome.
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Kranz et al. Genome Biology 2013 14:R112 doi:10.1186/gb-2013-14-10-r112