Additional file 1: Figure S1.

Correcting constitutive exons selection bias in non-tissue-dependent exons. Exon scores for being alternative versus constitutive (x-axis) are plotted as a cumulative distribution function (CDF, y-axis). The initial set of selected non-tissue-dependent exons (blue) was biased towards constitutive exons compared to a random sample of 1,000 exon triplets from the genome (red). Subsampling the original set of 2,000 exons per tissue to fit the score distribution of a random set gave a good fit (green). Both green and red line plots are accumulated over all exons in all tissues as no significant difference was observed between the different tissues.

Format: PDF Size: 125KB Download file

This file can be viewed with: Adobe Acrobat Reader

Barash et al. Genome Biology 2013 14:R114   doi:10.1186/gb-2013-14-10-r114