Additional file 1: Figure S1.
Correcting constitutive exons selection bias in non-tissue-dependent exons. Exon scores for being alternative versus constitutive (x-axis) are plotted as a cumulative distribution function (CDF, y-axis). The initial set of selected non-tissue-dependent exons (blue) was biased towards constitutive exons compared to a random sample of 1,000 exon triplets from the genome (red). Subsampling the original set of 2,000 exons per tissue to fit the score distribution of a random set gave a good fit (green). Both green and red line plots are accumulated over all exons in all tissues as no significant difference was observed between the different tissues.
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Barash et al. Genome Biology 2013 14:R114 doi:10.1186/gb-2013-14-10-r114