The majority of genes show the same XCI status in all informative sample sets. X-linked genes are mostly subject to XCI (red), show variable escape (purple) or escape from XCI (green) in all sample sets. Three classes of genes show a different XCI status in at least one informative sample set: population-specific XCI (orange), cell line-specific XCI (blue) and inconsistent XCI across the informative sample sets (white). At least five females were required to be informative in each informative sample set for a gene to be considered as differing between sample sets. Novel genes are included within the 'all genes’. The decision tree used to classify genes is shown in Additional file 13.
Cotton et al. Genome Biology 2013 14:R122 doi:10.1186/gb-2013-14-11-r122