Additional file 13: Figure S5.
Decision tree to determine XCI status across sample sets. In order to compare XCI status between the three sample sets a standard set of yes/no questions was devised. To begin (black rectangle in the center) the two LCL sample sets (CEU and YRI) are examined, then the FIB sample set is brought in to determine if differences in XCI status were the result of population or cell line differences. In total, six different cross-sample set XCI statuses were defined: subject in all sample sets (red), VE (variable escape) in all sample sets (purple), escape in all sample sets (green), population-specific XCI (orange), cell line-specific XCI (blue), population and cell line-specific XCI (blue and orange stripes) and inconsistent XCI between samples sets (white).
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Cotton et al. Genome Biology 2013 14:R122 doi:10.1186/gb-2013-14-11-r122