CpG Content in L. albipes. (A) Exons and mRNAs have lower CpG than expected, suggesting that gene bodies may be preferentially methylated in L. albipes, consistent with previous findings in A. mellifera. (B) GpC ratios were also calculated as a control. GpC dinucleotides have the same sequence composition as CpGs, but are not subject to biased mutation rates due to DNA methylation.
Kocher et al. Genome Biology 2013 14:R142 doi:10.1186/gb-2013-14-12-r142