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Open Access Research

The evolution, impact and properties of exonic splice enhancers

Eva Fernández Cáceres and Laurence D Hurst*

Author Affiliations

Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK

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Genome Biology 2013, 14:R143  doi:10.1186/gb-2013-14-12-r143

Published: 20 December 2013

Additional files

Additional file 1: Table S1:

The hexamers that feature in the various intersection datasets.

Format: XLSX Size: 191KB Download file

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Additional file 2: Table S2:

Deviation of each raw dataset in the intersection datasets from null expectation measured as a Z score.

Format: XLS Size: 31KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 3: Table S3:

HPI scores for all codons given each ESE dataset.

Format: CSV Size: 10KB Download file

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Additional file 4: Table S4a:

Partial spearman correlations for the instances where exons are flanked by introns of any size.

Format: XLS Size: 34KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 5: Table S5:

Raw correlations between ESE density and seven possible predictive variables.

Format: XLS Size: 20KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 6: Table S4b:

Partial spearman correlations for the instances where exons are flanked by introns smaller than 1,500 bp.

Format: XLS Size: 34KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 7: Figure S1:

Information content across the hexamers in each dataset.

Format: PDF Size: 5KB Download file

This file can be viewed with: Adobe Acrobat Reader

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