Research highlight
A CRISPR way to engineer the human genome
Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins Medical Institutions, 615 North Wolfe Street, Baltimore, MD 21205, USA
Genome Biology 2013, 14:107 doi:10.1186/gb-2013-14-2-107
Published: 26 February 2013Abstract
RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an efficient and versatile method for targeted manipulation of mammalian genomes.
