The fractured genome of HeLa cells
1 Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA
2 Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24060, USA
3 Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Genome Biology 2013, 14:111 doi:10.1186/gb-2013-14-4-111Published: 17 April 2013
Whole-genome sequencing of the widely used HeLa cell line provides a nucleotide-resolution view of a greatly mutated and in some places shattered genome.