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Research highlight

The complex binding of PRDM9

Laure Ségurel

Author affiliations

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA

Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA

Citation and License

Genome Biology 2013, 14:112  doi:10.1186/gb-2013-14-4-112

Published: 24 April 2013

Abstract

A recent study investigates the in vitro DNA binding behavior of PRDM9, a zinc finger protein involved in the localization of recombination hotspots in mammals.

Please see related research article: http://genomebiology.com/2013/14/4/R35 webcite

Keywords:
DNA binding; hotspots; meiotic recombination; PRDM9; zinc finger