Table 3

Multivariable survival analysis with immune metagenes in the high proliferation tertile.

PH (n = 657)

Multivariate

Variables

Hazard ratio

(95% CI)2

P-value3


Model 1

B/P (L, I, H)1

0.72 (0.58 to 0.89)

0.003

T/NK (L, I, H)

0.73 (0.59 to 0.90)

0.003

Model 2

B/P (L, I, H)

0.73 (0.62 to 0.89)

0.002

M/D (L, I, H)

0.70 (0.57 to 0.85)

0.0004

Model 3

T/NK (L, I, H)

0.77 (0.60 to 0.99)

0.04

M/D (L, I, H)

0.70 (0.55 to 0.90)

0.006

Model 4

B/P (L, I, H)

0.76 (0.61 to 0.94)

0.01

M/D (L, I, H)

0.75 (0.58 to 0.97)

0.03

T/NK (L, I, H)

0.88 (0.67 to 1.15)

0.34


1metagene tertiles (L: low; I: intermediate; H: high); 2 95%. B/P: B cell/plasma cell metagene; M/D: monocytes and dendritic cell metagene; T/NK: T cell and natural killer cell metagene.

Nagalla et al. Genome Biology 2013 14:R34   doi:10.1186/gb-2013-14-4-r34

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