Figure 3.

Enrichment of aDMPs by genomic location. Log-fold difference of enrichment (observed/expected frequency) in the aDMPs with P < 0.05 and delta beta >0.1 (n = 14,629) and >0.2 (n = 2,632) for specific genomic locations, grouped by association with genes, CpG islands, known DMRs and regulatory regions. Positive values indicate enrichment and negative values indicate depletion in the aDMP dataset. P-values: *P < 0.05; ** P < 1 × 10^-20, *** P < 1 × 10^-50.