Table 3

Ontology enrichment analysis for age-associated differentially methylated regions

GO term

Description

-log10 binomial P-value


GO:0048513

Organ development

17.68

GO:00048869

Cellular development process

15.59

GO:0030154

Cell differentiation

15.33

GO:0010033

Response to organic substance

14.47

GO:0009887

Organ morphogenesis

14.00

GO:0006359

Regulation of transcription from RNAs pol III promoter

9.66

GO:0000975

Regulatory region DNA binding

8.73

GO:0044212

Transcription regulatory region DNA binding

8.00

GO:0045945

Positive regulation of transcription from RNA pol III promoter

7.51

GO:0048598

Embryonic morphogenesis

6.80

GO:0016480

Negative regulation of transcription from RNA pol III promoter

6.67

GO:0003205

Cardiac chamber development

5.71

GO:0030326

Embryonic limb morphogenesis

4.4

GO:0060173

Limb development

3.82

GO:0035108

Limb morphogenesis

3.62

GO:0048546

Digestive tract morphogenesis

3.10


Gene Ontology (GO) terms significant at an adjusted P-value <0.05 [81] are shown.

Martino et al. Genome Biology 2013 14:R42   doi:10.1186/gb-2013-14-5-r42

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