Figure 2.

Volcano plots of the distributions of the P-values resulting from the Wilcoxon signed-rank test versus the corresponding mean β-value difference for each CpG position. (a) Unadjusted data (72 CpG sites had a P-value <0.01 and mean β-value difference >0.05). (b) Data adjusted for buccal epithelium content using the PTPN7 CpG (131 CpG sites had a P-value <0.01 and mean β-value difference >0.05; pair 1 was excluded).