Table 5

Sequencing technology error rates

Data set

Fractional error rate



Sample

#

Platform

Mismatches

Deletions

Insertions

Total


P. falciparum

1

Illumina MiSeq

0.0046

0.00021

0.00011

0.0049

2

Ion Torrent PGM

0.0038

0.0090

0.0068

0.020

3

Pacific Biosciences RS

0.0068

0.033

0.14

0.18

E. coli

4

Illumina MiSeq

0.0036

0.0000097

0.0000051

0.0037

5

Ion Torrent PGM

0.0018

0.0053

0.0044

0.012

6

Pacific Biosciences RS

0.0077

0.032

0.17

0.21

R. sphaeroides

7

Illumina MiSeq

0.0030

0.000018

0.0000089

0.0030

8

Ion Torrent PGM

0.0014

0.0055

0.0037

0.011

9

Pacific Biosciences RS

0.0076

0.029

0.16

0.20

Human

14

Illumina HiSeq

0.0030

0.00023

0.00017

0.0034

15

Ion Torrent PGM

0.0060

0.0069

0.0057

0.019

16

Complete Genomics

0.023

0.000099

0.000091

0.024


For a subset of the data sets in Table 2, we show the fractional rates of mismatch, deletion, and insertion, computed relative to coverage, inferred by comparison to the reference sequences. For human we note that bona fide differences between the sample and reference sequence were recorded as errors.

Ross et al. Genome Biology 2013 14:R51   doi:10.1186/gb-2013-14-5-r51

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