The advantages of SMRT sequencing
1 New England Biolabs, 240 County Road, Ipswich, MA 01938, USA
2 Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA
3 Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11743, USA
Genome Biology 2013, 14:405 doi:10.1186/gb-2013-14-7-405Published: 3 July 2013
Of the current next-generation sequencing technologies, SMRT sequencing is sometimes overlooked. However, attributes such as long reads, modified base detection and high accuracy make SMRT a useful technology and an ideal approach to the complete sequencing of small genomes.