Table 2

Frequency of deformities and lethality in egfp TAL-injected embryos

Targeting nuclease(s)

Wild type

Abnormal

Dead

Total (N)

12.5 pg egfp5TAL

86 (93.5%)

6 (6.5%)

0 (0%)

92

25 pg egfp5TAL

14 (23.0%)

44 (72%)

3 (4.9)

61

12.5 pg egfp3TAL

89 (96.7%)

2 (2.2%)

1 (1.1%)

92

25 pg egfp3TAL

53 (61.6%)

28 (32.6%)

5 (58.0%)

86

12.5 pg egfp5TAL+egfp3TAL

202 (82.8%)

29 (11.9%)

13 (5.3%)

244

25 pg egfp5TAL+egfp3TAL

40 (33.1%)

62 (51.2%)

19 (15.7%)

121

Numbers were tabulated from at least two independent experiments.

Lim et al. Genome Biology 2013 14:R69   doi:10.1186/gb-2013-14-7-r69