Concordance of sQTLs in two RNA-seq datasets of the Caucasian (CEU) population as obtained by different statistical models. (a) Comparison of GLiMMPS P values for the most significant SNP of each alternatively spliced exon in the CEU and CEU2 datasets. X-axis shows the -log10(P value) in CEU. Y-axis shows the -log10(P value) in CEU2. Red lines show the FDR cutoff of 10%. (b) Concordance of sQTL rankings between CEU and CEU2 based on different statistical models. The x-axis represents the number of top n ranked sQTLs in each dataset, while the y-axis represents the percentage of sQTLs in common between the two datasets among the top n sQTLs in CEU, based on P value rankings calculated by the linear model (lm), generalized linear model (glm), and GLiMMPS.
Zhao et al. Genome Biology 2013 14:R74 doi:10.1186/gb-2013-14-7-r74