Table 1 |
||||||
|
Overview of the blood samples analyzed using NGS and RT-qPCR |
||||||
|
Sample group |
N |
Age (mean ± SD) |
Sex (female/male) |
MMSE (mean ± SD) |
Cohort size NGS |
Cohort size RT-qPCR |
|
|
||||||
|
AD |
106 |
72.7(10.4) |
53/53 |
18.9 (3.4) |
48 |
94 |
|
|
||||||
|
Healthy control |
22 |
67.1 (7.5) |
11/11 |
29.3 (1.2) |
22 |
21 |
|
|
||||||
|
Mild cognitive impairment |
18 |
73.9 (6.2) |
9/9 |
25.3 (1.4) |
- |
18 |
|
|
||||||
|
Multiple sclerosis |
16 |
32.3 (10.7) |
12/4 |
NA |
- |
16 |
|
|
||||||
|
PD |
9 |
69.7 (9.0) |
1/8 |
25.2 (4.2) |
- |
9 |
|
|
||||||
|
DEP |
15 |
45.2 (9.1) |
0/15 |
NA |
- |
15 |
|
|
||||||
|
BD |
15 |
41.9 (13.7) |
14/1 |
29.5 (1.6) |
- |
15 |
|
|
||||||
|
SCHIZ |
14 |
41.7 (7.9) |
1/13 |
26.1 (4.3) |
- |
14 |
|
|
||||||
|
AD: Alzheimer disease; BD: bipolar disorder; DEP: major depression; MMSE: Mini-Mental State Exam; NA: not available; NGS: next-generation sequencing; PD: Parkinson's disease; RT-qPCR: quantitative real-time PCR; SCHIZ: schizophrenia. |
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|
Leidinger et al. Genome Biology 2013 14:R78 doi:10.1186/gb-2013-14-7-r78 |
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