Table 2 |
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Summary of the SVM classifications containing the means, standard deviations, and 95% confidence intervals (CI) of the accuracy (acc), specificity (spec), sensitivity (sens) running 100 repetitions of 10-fold cross-validations with linear kernel. |
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Comparison |
Classification |
Permutation test |
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|
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Acc |
Spec |
Sens |
Acc |
Spec |
Sens |
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|
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AD vs. control |
93.3% ± 4.6 CI:92.4-94.2% |
95.1% ± 5.4 CI:94.1-96.2% |
91.5% ± 5.8 CI:90.4-92.7% |
50.7% ± 12.5 CI:48.2-53.1% |
50.7% ± 13.3 CI:48.1-53.3% |
50.7% ± 14.1 CI:47.9-53.4% |
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|
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MCI vs. control |
84.2% ± 3.7 CI:83.4-84.9% |
81.1% ± 5.6 CI:80.0-82.2% |
87.7% ± 3.7 CI:87.0-88.5% |
51.3% ± 11.4 CI:49.0-53.5% |
52.0% ± 12.2 CI:50.0-54.4% |
50.4% ± 13.5 CI:47.8-53.1% |
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|
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PSY vs. control |
97.1% ± 1.6 CI:96.8-97.4% |
95.3% ± 1.7 CI:95.0-95.6% |
99.0% ± 2.4 CI:98.5-99.4% |
48.7% ± 10.6 CI:46.7-50.8% |
48.5% ± 12.4 CI:46.0-50.9% |
49.0% ± 12.1 CI:46.6-50.8% |
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|
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Other ND vs. control |
82.8% ± 5.0 CI:81.8-83.7% |
84.0% ± 5.8 CI:83.0-85.2% |
81.4% ± 6.7 CI:80.1-82.7% |
50.3% ± 10.3 CI:48.3-52.3% |
50.7% ± 11.7 CI:48.4-53.0% |
50.0% ± 12.0 CI:47.6-52.3% |
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|
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NEURO vs. control |
86.1% ± 5.7 CI:85.0-87.2% |
88.7% ± 6.8 CI:87.3-90.0% |
83.6% ± 6.6 CI:82.3-84.9% |
49.9% ± 10.8 CI:47.8-52.1% |
50.1% ± 11.5 CI:47.9-52.3% |
49.8% ± 13.3 CI:47.2-52.3% |
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AD vs. MCI |
75.6% ± 7.8 CI:74.1-77.2% |
76.7% ± 8.3 CI:75.1-78.4% |
74.6% ± 9.7 CI:72.7-76.5% |
50.6% ± 9.4 CI:48.7-52.4% |
51.2% ± 10.4 CI:49.1-53.2% |
49.9% ± 11.7 CI:47.7-52.2% |
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AD vs. PSY |
77.8% ± 4.0 CI:77.0-78.5% |
76.3% ± 4.8 CI:75.4-77.3% |
79.2% ± 5.4 CI:78.1-80.2% |
50.0% ± 8.0 CI:48.5-51.6% |
49.1% ± 9.3 CI:47.3-50.9% |
51.1% ± 10.3 CI:49.1-53.1 |
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AD vs. other ND |
73.8% ± 4.4 CI:72.9-74.7% |
75.2% ± 4.7 CI:74.2-76.1% |
72.4% ± 6.4 CI:71.2-73.7% |
50.1% ± 7.3 CI:48.7-51.5% |
49.2% ± 9.4 CI:47.4-51.1% |
51.0% ± 8.5 CI:49.3-52.7% |
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The right part of the table contains the results for the permuted class labels. PSY = psychological disorders (DEP, BD, SCHIZ), other ND = other neurodegenerative disorders (PD, MS, MCI), NEURO = PSY + other ND |
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|
Leidinger et al. Genome Biology 2013 14:R78 doi:10.1186/gb-2013-14-7-r78 |
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