Resolution:
standard / ## Figure 6.
PARma model for replicate A of the DG75 experiment. The conversion model in red represents the conditional propensity that a base becomes
cross-linked given there is a uridine at the corresponding position. Note that the
propensity is only known up to a constant factor and arbitrarily scaled to a mode
of 1. The blue and green lines illustrate the 3' and 5' cleavage models, respectively.
These correspond to the conditional probabilities that the RNase Tl cleavage site
is at a certain position or closer to the seed site given that there is a guanine.
The model shows that the observations made for a few visually inspected validated
target sites are also true globally for many clusters.
Erhard |