Pattern of evolutionary conservation of the three enhancers driving miniature expression in trichome cells. The position of epidermal enhancers is shown by cyan boxes and their respective architectures with respect to svbF7 (red), blue and yellow motifs are schematized across Drosophila species. Orthologous sequences were identified by BLAST and manually adjusted for optimized alignment. Motif search was performed in individual sequences taken independently, using the same threshold for each motif in all cases. Bottom histograms represent the pattern of evolutionary conservation across Drosophila species, focusing on individual regions harboring identified cis-regulatory motifs (color coded).
Menoret et al. Genome Biology 2013 14:R86 doi:10.1186/gb-2013-14-8-r86