Open Access Method

Virmid: accurate detection of somatic mutations with sample impurity inference

Sangwoo Kim1*, Kyowon Jeong2, Kunal Bhutani1, Jeong Ho Lee36, Anand Patel1, Eric Scott3, Hojung Nam4, Hayan Lee5, Joseph G Gleeson3 and Vineet Bafna1*

Author Affiliations

1 Department of Computer Science and Engineering, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA

2 Department of Electrical and Computer Engineering, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA

3 Institute for Genomic Medicine, Rady Children's Hospital, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA

4 School of Information and Communications, Gwangju Institute of Science and Technology, 123 Cheomdangwagi-ro, Buk-gu, Gwangju, 500-712, Republic of Korea

5 Department of Computer Science, Stony Brook University, 100 Nicolls Road, NY 11794, USA

6 Graduate School of Medical Science and Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea

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Genome Biology 2013, 14:R90  doi:10.1186/gb-2013-14-8-r90

Published: 29 August 2013

Additional files

Additional file 1:

Supplementary information. A supplementary Portable Document File (PDF) that includes supplementary figures (Figures S1 to S4), tables (Tables S1 and S2) and methods (supplementary notes 1 to 5 including mathematical proofs, derivations and model descriptions).

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