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Review

Toward knowledge support for analysis and interpretation of complex traits

Nigel Collier12*, Anika Oellrich3 and Tudor Groza4

Author Affiliations

1 European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

2 National Institute of Informatics, Tokyo 101-8430, Japan

3 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

4 School of ITEE, The University of Queensland, St Lucia, QLD 4072, Australia

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Genome Biology 2013, 14:214  doi:10.1186/gb-2013-14-9-214

Published: 30 September 2013

Abstract

The systematic description of complex traits, from the organism to the cellular level, is important for hypothesis generation about underlying disease mechanisms. We discuss how intelligent algorithms might provide support, leading to faster throughput.