Linear regression results showed an association between DNA methylation and age across four human tissues. (A) Uniform quantile-quantile (Q-Q) plots of -log P-values from linear regression tests for associations between β-score and age within blood, brain, kidney, and skeletal muscle tissue samples. (B) Scatterplots for the top five strongest associations between β-score and age across each of the four tissues. Illumina CpG ID, P-value, and R-squared results are depicted above each scatterplot.
Day et al. Genome Biology 2013 14:R102 doi:10.1186/gb-2013-14-9-r102