Table 4

Number of unique and shared ageCGs/genes affiliated with genes expressed within tissuesa
Unique ageCGs/genesb Shared ageCGs/genesc P-valued
Expressed Non-expressed Expressed Non-expressed
Blood 13 (65.0) 7 (35.0) 8 (22.9) 27 (77.1) 0.003 *
Brain 16 (72.7) 6 (27.3) 27 (75.0) 9 (25.0) 0.766
Kidney 82 (78.8) 22 (21.2) 17 (56.7) 13 (43.3) 0.019
Muscle 84 (88.4) 11 (11.6) 11 (42.3) 15 (57.7) 3.40 × 10-6 *

aExpressed genes, FPKM > 0.25; non-expressed genes, FPKM < 0.05. Parentheses indicate percentage of total in each CpG context category.

bUnique ageCGs/genes had q < 0.05 from linear regression results in one tissue and q > 0.5 for the same affiliated gene in the other three tissues.

cShared ageCGs/genes had q < 0.05 in all four tissues.

dResulting P-values from Fisher’s exact tests between the number of unique and shared, expressed or non-expressed ageCGs/genes within tissues.

*Significant P-values meet Bonferroni correction for multiple testing.

Day et al.

Day et al. Genome Biology 2013 14:R102   doi:10.1186/gb-2013-14-9-r102

Open Data