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Table 4 |
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| Number of unique and shared ageCGs/genes affiliated with genes expressed within tissuesa | |||||
| Unique ageCGs/genesb | Shared ageCGs/genesc | P-valued | |||
| Expressed | Non-expressed | Expressed | Non-expressed | ||
| Blood | 13 (65.0) | 7 (35.0) | 8 (22.9) | 27 (77.1) | 0.003 * |
| Brain | 16 (72.7) | 6 (27.3) | 27 (75.0) | 9 (25.0) | 0.766 |
| Kidney | 82 (78.8) | 22 (21.2) | 17 (56.7) | 13 (43.3) | 0.019 |
| Muscle | 84 (88.4) | 11 (11.6) | 11 (42.3) | 15 (57.7) | 3.40 × 10-6 * |
aExpressed genes, FPKM > 0.25; non-expressed genes, FPKM < 0.05. Parentheses indicate percentage of total in each CpG context category.
bUnique ageCGs/genes had q < 0.05 from linear regression results in one tissue and q > 0.5 for the same affiliated gene in the other three tissues.
cShared ageCGs/genes had q < 0.05 in all four tissues.
dResulting P-values from Fisher’s exact tests between the number of unique and shared, expressed or non-expressed ageCGs/genes within tissues.
*Significant P-values meet Bonferroni correction for multiple testing.
Day et al.
Day et al. Genome Biology 2013 14:R102 doi:10.1186/gb-2013-14-9-r102