Table 5
Descriptive features and enrichments of differentially methylated sites with age across human blood, brain, kidney, and skeletal muscle tissues
Positive ageCGs	Negative ageCGs
Within CGIs	Within CGSs, CGOs
Generally hypomethylated	Generally hypermethylated
Smaller relative slope magnitude	Larger relative slope magnitude
Greater enrichment in H3K27Me3	Less enrichment in H3K27Me3
More shared sites across tissues	More unique sites across tissues
Genes with lower relative FPKM	Genes with higher relative FPKM
Near development-related genes	Near tissue-specific regulated genes
Generally further from CTCF sites	Generally closer to CTCF sites
Enriched within LADs	Not enriched in LADs

Day et al.

Day et al. Genome Biology 2013 14:R102   doi:10.1186/gb-2013-14-9-r102