RMSD correlation between qRT-PCR and RNA-seq log2 expression changes computed by each method. Overall, there is good concordance between log2 values derived from the DE methods and the experimental values derived from qRT-PCR measures. Upper quartile normalization implemented in baySeq package is least correlated with qRT-PCR values. DE, differential expression; RMSD, root-mean-square deviation.
Rapaport et al. Genome Biology 2013 14:R95 doi:10.1186/gb-2013-14-9-r95