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Additional file 9.

Osteoclast differentiation scheme showing transcription factors that are known to be involved in monocyte-to-osteoclast differentiation. We have in red or blue the presence of binding motifs for those factors (according to TRANSFAC analysis) among the sequences surrounding the CpGs that become hypo- or hypermethylated. Those arising from our analysis are highlighted in red and blue (associated with hypermethylation and hypomethylation, respectively).

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de la Rica et al. Genome Biology 2013 14:R99   doi:10.1186/gb-2013-14-9-r99