Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
- Equal contributors
1 Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden
2 Department of Medical Sciences, Cancer Pharmacology and Computational Medicine, Uppsala University, Uppsala 75185, Sweden
3 Department of Human Genetics, McGill University, Montréal, Québec H3A0G1, Canada
4 Department of Medical Sciences, Rheumatology, Uppsala University, Uppsala 75185, Sweden
5 Department of Pediatrics, Tromsø University and University Hospital, Tromsø N-9038, Norway
6 Department of Medical Biosciences, University of Umeå, Umeå 90185, Sweden
7 Department of Women’s and Children’s Health, Pediatric Oncology, Uppsala University, Uppsala 75185, Sweden
8 Department of Pediatrics and Adolescence, Oulu University Hospital, Oulu 90029, Finland
9 Childhood Cancer Research Unit, Karolinska Institutet, Astrid Lindgren Children’s Hospital, Karolinska University Hospital, Stockholm 17176, Sweden
10 Pediatric Hematology-Oncology, Children’s Hospital, Barnaspitali Hringsins, Landspitali University Hospital, Reykjavik 101, Iceland
11 ediatrics and Adolescent Medicine, Rigshospitalet, and the Medical Faculty, Institute of Clinical Medicine, University of Copenhagen, Copenhagen 2100, Denmark
12 Division of Hematology-Oncology, CHU Sainte-Justine Research Center, Department of Pediatrics, University of Montreal, Montréal, Québec, Canada
13 Department of Human Genetics, McGill University and Genome Quebec Innovation Center, Montréal, Québec H3T1C5, Canada
14 For the Nordic Society of Pediatric Hematology and Oncology (NOPHO
Genome Biology 2013, 14:r105 doi:10.1186/gb-2013-14-9-r105Published: 24 September 2013
Additional file 1: Table S1:
(Tab delimited .txt) Probe-level annotations for the 485,577 probes on the 450k array, including a column denoting the 435,941 CpG sites analyzed in the current study. Columns representing the differentially methylated CpG (DMC) signatures are included.
Format: ZIP Size: 20MB Download file
Additional file 2: Tables S2 to S18:
Supplemental Tables S2 to S18.
Format: XLSX Size: 4.9MB Download file
Additional file 3: Figures S1 to S16:
Supplemental Figures S1 to S16.
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Additional file 4:
Supplemental materials and methods.
Format: DOCX Size: 37KB Download file